Figure 5.

Amphiregulin expression is up-regulated in adeno-associated virus (AAV)/hepatitis B virus (HBV)-infected livers. (a) Temporal change of amphiregulin expression in the serum and liver homogenate after AAV/HBV infection; n = 5 mice per group. (b) Amphiregulin mRNA level in different cell types. WBC, white blood cells. Each dot represents an individual mouse. (c) Amphiregulin concentration in cell lysates detected by ELISA. Cells were lysed as mentioned in the Materials and Methods. The supernatants of cell lysate were used for ELISA; n = 6 mice per group.*P < 0·05; **P < 0·01; ***P < 0·001.