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. 2015 Mar;144(3):530–539. doi: 10.1111/imm.12403

Figure 4.

Figure 4

Intact expression of activating receptors and tumour cell-evoked natural killer (NK) cell activation during human α1-antitrypsin (hAAT) treatment. (a, b) C57BL/6 mice were given hAAT at indicated doses or PBS (n = 3 per group). Expression of the membranal activating receptors NKp46 and NKG2D was examined in splenic NK cells. (c–e) Poly(I:C)-treated NK cells were co-cultured with (c) YAC1 cells, (d) MIN-6 insulinoma cells or (e) B16-F10 melanoma cells in the presence or absence of 0·5 mg/ml hAAT for 3 hr. CD107a+ cells out of NK1.1+ cells. Mean ± SEM.