Figure 5.

Multiple low-dose streptozotocin (MLD-STZ) : α1-antitrypsin (hAAT) treatment and natural killer (NK) cell depletion. Mice were subjected to MLD-STZ. Groups received either PBS or α-GM1 antibody or hAAT (1 mg per animal). The hAAT treatment started 1 day before STZ injections and α-GM1 was started 3 days before STZ injections. Blood glucose and body weight, mean ± SEM, *P < 0·05 between control and α-GM1 group. GTT, glucose tolerance test, mean ± SEM, *P < 0·05 between control and hAAT group.