Table 2.

Prediction of survival and recurrence of patients with a single nodule of SHCC following curative resection

Factors	OS			TTR
	Univariate multivariate			Univariate multivariate
	P	HR (95 % CI)	P	P	HR (95 % CI)	P
Age (≤53 vs >53)	NS		NA	0.004		NS
AFP(≤20 vs >20)	NS		NA	0.043		NS
INR (≤1.0 vs >1.0)	0.010		NS	NS		NA
PLT counts (≤127 vs >127)	0.046		NS	NS		NA
Neutrophil counts	0.040	0.329 (0.174–0.623)	0.001	NS		NA
Vascular invasion (yes vs no)	NS		NA	0.001	1.757 (1.110–2.781)	0.016
Tumor size (≤3.0 vs >3.0)	0.040		NS	<0.001		NS
Postoperative TACE (yes vs no)	0.001	2.566 (1.488–4.424)	0.001	<0.001	2.175 (1.408–3.359)	<0.001
Re-operation (yes vs no)	NS		NA	<0.001	9.037 (4.970–16.432)	<0.001
NLR (>2.1 vs ≤2.1)	0.014	3.013 (1.633–5.561)	<0.001	0.002	1.619 (1.057–2.478)	0.027

Univariate analysis Kaplan-Meier method, Multivariate analysis Cox proportional hazards regression model, SHCC small hepatocellular carcinoma, AFP alpha-fetoprotein, INR international normal ratio, PLT platelet, TACE transarterial chemoembolization, NLR neutrophil-to-lymphocyte ratio, OS overall survival, TTR time to recurrence, HR hazard ratio, NS not significant, NA not adopted