Table 1.
Baseline characteristics of the study population
| Study A (574) | Study B (251) | |||
|---|---|---|---|---|
| Mean/N | SD/% | Mean | SD/% | |
| Age (years) | 52 | 12.2 | 50.9 | 12.9 |
| Female | 224 | 61 | 102 | 40.6 |
| White | 52 | 9.1 | 13 | 5.2 |
|
Smoking Status | ||||
| Regularly | 55 | 10.7 | 28 | 12.2 |
| Occasionally | 281 | 54.5 | 111 | 48.3 |
| Never | 139 | 24.2 | 59 | 23.5 |
| Systolic Blood Pressure (mm Hg) | 131.4 | 17.5 | 133.1 | 17.7 |
| Diastolic Blood Pressure (mm Hg) | 81.0 | 10.0 | 80.9 | 10.3 |
|
Etiology of Kidney Disease | ||||
| Polycystic Kidney Disease | 139 | 24.2 | 59 | 23.5 |
| Hereditary Nephritis and Tubulointerstitial | 175 | 30.5 | 74 | 29.5 |
| Disease | ||||
| Hypertensive Kidney Disease | 100 | 17.4 | 39 | 15.5 |
| Diabetic Nephropathy | 17 | 3 | 9 | 3.6 |
| Glomerular Disease | 143 | 24.9 | 70 | 27.9 |
|
Laboratory Data | ||||
| Serum Creatinine | 1.9 | 0.5 | 3.4 | 0.9 |
| (mg/dl) Serum Cystatin C (mg/l) | 1.9 | 0.4 | 3.0 | 0.5 |
| Measured GFR (ml/min/1.73 m2) | 38.6 | 8.9 | 18.5 | 3.4 |
| Proteinuria (g/day) | 1.0 | 1.6 | 1.4 | 1.7 |
| Serum Albumin (g/dl) | 4.0 | 0.3 | 4.0 | 0.4 |
| Serum CRP (mg/l) | 0.5 | 0.6 | 0.4 | 0.6 |
| Estimated Protein | 1.1 | 0.2 | 0.9 | 0.2 |
| Intake (g/kg/day)** | ||||
* Data are presented as mean +/−SD for continuous variables and N/percentage for categorical variables
**
Protein intake estimated from urine urea nitrogen excretion rate was available for 741/825 participants