Table 2.
N | Not adjusted | Adjusted for GFR | Adjusted for GFR Measurement Error (0.015) | Adjusted for GFR Measurement Error (0.015), age, sex and race** | |||||
---|---|---|---|---|---|---|---|---|---|
Coeff (SD) | p-value | Coeff (SD) | p-value | Coeff (SD) | p-value | Coeff (SD) | p-value | ||
Serum Creatinine (%) | 741 | −0.141 (0.010) | <0.001 | −0.006 (0.008) | 0.45 | 0.012 (0.008) | 0.145 | 0.024 (0.006) | <0.001 |
Serum Cystatin C (%) | 741 | −0.11 (0.009) | <0.001 | −0.007 (0.006) | 0.26 | 0.022 (0.006) | <0.001 | 0.009 (0.006) | 0.13 |
Protein intake is estimated from urine urea nitrogen, cystatin and creatinine are log transformed.
Interpretation: After adjustment for GFR, age, race and sex, and GFR measurement error, a 0.2 g/kg/day increase in baseline protein intake is associated with a 2.4 (0.6) % higher baseline serum creatinine and a 0.9 (0.6) % higher baseline serum cystatin C.