Fig. 3.

Analysis of transcriptional activity in the −952 to +17 region of human TXN promoter. HuH-7 cells were transiently transfected with 1 mg of luciferase reporter constructs and 50 ng of a promoter less renilla plasmid. Luciferase activity was normalized against the values of the renilla internal control. The data represent mean ± SEM (n = 3) and are expressed as fold-induction with respect to the empty vector (pGL3basic). *p < 0.005 with the TXN c.-793T and TXN c.-793C constructs