Table 1.
Characteristics of selected polymorphisms
| HGN | Gene name | dbSNPa | Tag-SNPb | Chr position | Referencec | MAFd |
|---|---|---|---|---|---|---|
| CAT | Catalase | rs1049982 | Y | 11:34417117 | c.-20C > T | 0.36 |
| SOD3 | Superoxidedismutase 3 | rs2536512 | Y | 4:24410413 | c.172G > A (p.A58T) | 0.37 |
| GPX1 | Glutathione peroxidase 1 | rs3448 | Y | 3:49371755 | c.*891C > T | 0.25 |
| TXN | Thioredoxin | rs4135168 | Y | 9:112056706 | c.24 + 1807G > A | 0.12 |
| rs2301241 | Y | 9:112059329 | c.-793T > C | 0.48 | ||
| XDH | Xanthine dehydrogenase | rs17323225 | 2:31446769 | c.1936T > C (p.I646V) | 0.06 | |
| COMT | Catechol-O-methyltransferase | rs740603 | Y | 22:19945177 | c.-91-3545G > A | 0.39 |
HGN HUGO gene nomenclature, Chr chromosome
aNCBI dbSNP Build 126
bTag-SNP by HapMap in Caucasoid subjects (Y yes)
cBegins in the first nucleotide 5′ of the ATG start codon, Build 126, Ensembl release 41 as suggested by the Human Gene Nomenclature Committee (HGNC)
dMAF (minor allele frequency), data obtained from 1000 genomes