Table 1.
Baseline characteristics and vascular risk factors in patients with leukoaraiosis (LA) and control group
| LA group (n = 30) | Control group (n = 30) | p-value | |
|---|---|---|---|
| Age | 58 years (SD 7) | 55 years (SD 6) | 0.08 |
| Men | 17 (56.7 %) | 20 (66.7 %) | 0.60 |
| Current smoker | 5 (16.7 %) | 5 (16.7 %) | 0.64 |
| Hypertension | 19 (63.3 %) | 16 (53.3 %) | 0.60 |
| Dyslipidemia | 13 (43.3 %) | 16 (53.3 %) | 0.61 |
| Minor stroke/TIA | 13 (43.3 %) | 0 (0.0 %) | <0.01 |
| Lacunar infarction | 9 (30.0 %) | 0 (0.0 %) | <0.01 |
| Major ischaemic infarction | 1 (3.3 %) | 1 (3.3 %) | 0.45 |
| Focal neurological deficits | 13 (43.3 %) | 4 (13.3 %) | 0.04 |
| Gait disturbance | 12 (40.0 %) | 2 (6.7 %) | 0.01 |
| Carotid plaques | 16 (53.3 %) | 10 (33.3 %) | 0.19 |
| Ischaemic heart disease | 3 (10.0 %) | 2 (6.7 %) | 0.60 |
| Antihypertensive therapy | 19 (63.3 %) | 15 (50.0 %) | 0.44 |
| Statin therapy | 14 (46.7 %) | 9 (30.0 %) | 0.29 |
| Antiplatelet therapy | 20 (66.7 %) | 7 (23.3 %) | <0.01 |
| Systolic blood pressure | 145.6 mmHg (SD 20.9) | 140.1 mmHg (SD 15.0) | 0.25 |
| Diastolic blood pressure | 88.7 mmHg (SD 10.1) | 84.2 mmHg (SD 8.9) | 0.07 |
| Body mass index | 27.8 kg/m2 (SD 4.4) | 29.0 kg/m2 (SD 5.4) | 0.37 |
| Intima-media thickness | 0.74 mm (SD 0.11) | 0.72 mm (SD 0.11) | 0.52 |
TIA indicates transient ischaemic attack; SD standard deviation