Table 3.

GO analysis of the mRNA-Seq-identified up-regulated transcripts.

GO_term	Cluster frequency	Background frequency	P value
Tricarboxylic acid cycle	6 out of 56 genes	16 out of 6525	4.9E−07
Cellular respiration	8 out of 56 genes	95 out of 6525	2.6E−04
Oxidation–reduction process	15 out of 56 genes	418 out of 6525	3.0E−04
Aerobic respiration	7 out of 56 genes	71 out of 6525	4.4E−04
Energy derivation by oxidation of organic compounds	8 out of 56 genes	118 out of 6525	1.3E−03
Single-organism metabolic process	23 out of 56 genes	1073 out of 6525	2.1E−03
Generation of precursor metabolites and energy	8 out of 56 genes	135 out of 6525	3.6E−03
Monocarboxylic acid transport	4 out of 56 genes	25 out of 6525	1.2E−02
Small molecule metabolic process	15 out of 56 genes	633 out of 6525	4.3E−02

A CGD GO term analysis is shown of the 56 up-regulated transcripts identified by mRNA-Seq along with the specific function, the cluster frequency, the background frequency and the P value. The cluster frequency is the number of genes identified by mRNA-Seq within our dataset that are assigned to a specific GO function. The background frequency is the number of genes identified in a specific GO function within the Candida albicans transcriptome.