Table 2.

Patients’ data and summary of usage of BMSCs

	Used for	Date	BSI ID	DIN	Age	Gender	Classification	Tryptase (ng/mL)	Mast cell aggregates	% invovement
1	BRDU proliferation assay	3/31/10			56	M	Smoldering	341	yes	50
2	clotted	7/28/10			40	M	Indolent	20	yes	10
3	clotted	6/9/11			65	M	Indolent	74	yes	5
4	clotted	5/12/11			51	F	Indolent	188	yes	30
5	did not grow	9/8/10			49	F	Indolent	35	yes	5
6	did not grow	11/3/10			44	M	Indolent	105	yes	30
7	colonies for morphology	4/14/10			42	F	Smoldering	150	yes	40
8	colonies for morphology	11/15/07			48	F	Indolent	287	yes	40
9	FACS analysis, repopulation assay	5/5/10			63	F	Indolent	52	yes	15
10	repopulation assay	6/9/10			58	F	indolent	29	yes	10
11	repopulation assay	4/21/10			67	M	Indolent	123	yes	40
12	frozen, ossicle	7/1/10			37	F	Indolent	46	yes	30
13	frozen, ossicle	7/7/10			66	F	No mastocytosis	17	no	0
14	frozen, ossicle	8/18/10			51	F	Indolent	68	yes	30
15	frozen, ossicle	7/14/10			61	F	Smoldering	319	yes	30
16	gene array	1/20/11	MC000299	11FC00007	23	F	2 minor criteria	10	no	<5
17	gene array	2/17/11	MC000304	11FC00024	41	F	Indolent	13	yes	20
18	gene array	3/30/11	MC000328	11FC00048	47	F	Indolent	25	yes	15
19	gene array	3/2/11	MC000306	11FC00031	57	M	Indolent	68	yes	10
20	gene array	3/31/11	MC000329	11FC00049	40	F	Indolent	79	yes	15
21	gene array	1/5/11		11FC00001	24	F	Indolent	80	yes	15
22	gene array	1/13/11		11FC00003	27	F	Indolent	100	yes	50
23	gene array	2/9/11	MC000303	11FC00020	55	F	Smoldering	119	yes	30
24	gene array	3/10/11	MC000318	11FC00038	58	F	Aggressive	120	yes	40
25	gene array	2/2/11		11FC00015	48	F	Smoldering	166	yes	50
26	gene array	3/3/11	MC000307	11FC00032	71	F	indolent	173	yes	30
27	normal and abnormal colonies, adipo and ostegenic assay	8/26/10			45	F	2 minor criteria	6	no	scattered mast cells
28	normal and abnormal colonies, adipo and ostegenic assay	9/2/10			43	F	Indolent	17	yes	20
29	normal and abnormal colonies, adipo and ostegenic assay	9/9/10			52	M	Indolent	24	yes	15
30	normal and abnormal colonies, adipo and ostegenic assay	11/10/10			36	F	Indolent	35	yes	5
31	normal and abnormal colonies, adipo and ostegenic assay	10/27/10			32	F	Smoldering	215	yes	35
32	normal and abnormal colonies, adipo and ostegenic assay	11/18/09			48	M	Indolent	65	yes	5

	>25% Spindle shaped	CD2	CD25	KIT mutation	Cytopenia	Hepatosplenomegaly	Osteopenia/Osteoporosis	Cytoreductive Treatment
1	yes	+	+	KIT D816V	no	yes	yes
2	yes	+	+	KIT D816V	no	no	no
3	yes	+	+	KIT D816V	thrombocytopenia	no	no
4	yes	+	+	KIT D816V	no	no	osteoporosis	colon CA s/p R hemicolectomy with adjuvant chemotherapy
5	yes	+	+	KIT D816V	no	splenomegaly	yes
6	yes	+	+	KIT D816V	no	no	osteoporosis
7	yes	+	+	KIT D816V	no	yes	no
8	yes	+	+	KIT D816V	eosinophilia	splenomegaly/hepatomegaly	osteoporosis
9	yes	+	+	KIT D816V	no	hepatomegaly	yes
10	yes	+	+	KIT D816V	no	no	yes
11	yes	+	+	KIT D816V	no	no	no
12	yes	+	+	KIT D816V	no	no	no
13	no	−	−	-	no	no	no
14	yes	+	+	KIT D816V	no	no	no
15	yes	+	+	KIT D816V	thrombocytosis	no	yes
16	yes	−	+	-	no	no	osteopenia
17	yes	+	+	-	no	no	no
18	yes	+	+	KIT D816V	no	no	no	imatinib
19	yes	+	+	KIT D816V	no	no	no
20	yes	+	+	KIT D816V	no	no	no
21	yes	+	+	KIT D816V	no	no	osteopenia
22	no	−	−	KIT K5091 germline	no	no	no
23	yes	+	+	KIT D816V	leukopenia	splenomegaly/hepatomegaly	no
24	yes	+	+	KIT D816V/KRAS G12D	thrombocytopenia	splenomegaly	no
25	yes	+	+	KIT D816V	no	hepatomegaly	no	IFN alpha
26	yes	+	+	KIT D816V	no	no	no
27	yes	−	+	-	no	no	no
28	yes	−	−	KIT D816V	no	no	no
29	yes	+	+	KIT D816V	no	no	yes
30	yes	+	+	KIT D816V	no	no	no
31	yes	+	+	KIT D816V	no	no	no
32	yes	+	+	KIT D816V	no	no	yes