Table 2. Multivariable regression analysis of dependent variable (Y) on independent variable (X).
Columns include adjusting variables (in addition to age and sex), parameter or slope estimate (ß), standard error (SE), and P value (test of slope = 0) for analyses done within stone former and control groups, Also given is the P value for the interaction term (test for common slopes) between X and stone group from similar models pooling stone-formers and controls. CSF = confirmed Ca stone formers; TSF = total stone formers (confirmed plus presumed).
| Dependent (Y) Variable | Independent (X) variable | Adjusted Variable | C, N = 201,ß (SE), P | CSF, N = 93,ß (SE), P | P, Interaction Term | TSF, N = 149, ß (SE), P | P, Interaction |
|---|---|---|---|---|---|---|---|
| S Ca | PTH | -0.006 (0.002), 0.036 | -0.006 (0.003), 0.017 | 0.66 | -0.006 (0.003), 0.017 | 0.66 | |
| S Ca | PTH | 1,25(OH)2D | -0.0005 (0.002), 0.04 | -0.006 (0.003), 0.018 | 0.94 | -0.006 (0.003), 0.018 | 0.87 |
| S Ca | 1,25(OH)2D | PTH | -0.00085 (0.03), 0.81 | -0.001 (0.003), 0.76 | 0.91 | -0.001 (0.003), 0.76 | 0.986 |
| S P | PTH | -0.092 (0.03), 0.09 | -0.089 (0.07), 0.17 | 0.77 | -0.002 (0.002), 0.315 | 0.226 | |
| S P | PTH | 1,25(OH)2D | -0.113 (0.05), 0.03 | -0.09 (0.06), 0.14 | 0.78 | -0.002 (0.002), 0.316 | 0.240 |
| S P | 1,25(OH)2D | PTH | 0.113 (0.05), 0.03 | 0.086 (0.07), 0.20 | 0.19 | 0.0001 (0.003), 0.968 | 0.18 |
| 1,25(OH)2D | PTH | 0.101 (0.05), 0.06 | 0.85 (0.07), 0.21 | 0.74 | 0.053 (0.052), 0.31 | 0.96 | |
| 1,25(OH)2D | PTH | FGF-23 | -0.163 (0.04), <0.001 | -0.035 (0.061), 0.56 | 0.050 | 0.06 (0.05), 0.32 | 0.73 |
| 1,25(OH)2D | PTH | FGF-23, S Ca | -0.168 (0.04), <0.001 | -0.05 (0.06), 0.46 | 0.084 | 0.05 (0.05), 0.33 | 0.73 |
| 1,25(OH)2D | PTH | FGF-23, S Ca, S P | -0.169 (0.04), <0.001 | -0.04 (0.06), 0.47 | 0.08 | 0.05 (0.05), 0.34 | 0.765 |
| 1,25(OH)2D | FGF-23 | -0.160 (0.04), <0.001 | -0.04 (0.06), 0.48 | 0.08 | -0.057 (0.034), 0.16 | 0.050 | |
| 1,25(OH)2D | FGF-23 | PTH | -0.168 (0.04), <0.001 | -0.05 (0.06), 0.38 | 0.51 | -0.05 (0.037), 0.11 | 0.045 |
| 1,25(OH)2D | FGF-23 | PTH, S Ca | -0.169 (0.04), <0.001 | -0.05 (0.06), 0.42 | 0.655 | -0.05 (0.037), 0.11 | 0.046 |
| 1,25(OH)2D | FGF-23 | PTH, S Ca, S P | -0.162 (0.04), <0.001 | -0.05 (0.06), 0.413 | 0.063 | -0.05 (0.037), 0.12 | 0.048 |
| 24,25(OH)2D | 25(OH)D | -0.00085 (0.03), 0.81 | -0.001 (0.003), 0.76 | 0.56 | 0.112 (0.006), <0.001 | 0.290 | |
| FePi% | PTH | 0.035 (0.019), 0.07 | 0.022 (0.024), 0.28 | 0.54 | 0.022 (0.024), 0.28 | 0.54 | |
| FePi% | PTH | 1,25(OH)2D | 0.035 (0.019), 0.052 | 0.027 (0.028), 0.336 | 0.50 | 0.027 (0.024), 0.26 | 0.50 |
| FePi% | PTH | 1,25(OH)2D, FGF23 | 0.031 (0.019), 0.09 | 0.028 (0.029), 0.35 | 0.51 | 0.028 (0.024), 0.25 | 0.51 |
| FePi% | 1,25(OH)2D | -0.026 (0.021), 0.2941 | -0.09 (0.04), 0.06 | 0.21 | -0.14 (0.04), 0.0009 | 0.017 | |
| FePi% | 1,25(OH)2D | PTH | -0.03 (0.024), 0.2028 | -0.009 (0.04), 0.048 | 0.19 | -0.108 (0.04), 0.0007 | 0.0204 |
| FePi% | 1,25(OH)2D | FGF23, PTH | -0.026 (0.025), 0.55 | -0.09 (0.05), 0.052 | 0.129 | -0.108 (0.04), 0.0045 | 0.018 |
| FePi% | 1,25(OH)2D | FGF23, PTH, SCa | -0.015 (0.026), 0.49 | -0.08(0.04), 0.060 | 0.13 | -0.108(0.04), 0.0046 | 0.018 |
| FePi % | FGF23 | 0.03 (0.01), 0.0092 | 0.009 (0.027), 0.724 | 0.1362 | 0.004 (0.0011), 0.8112 | 0.1362 | |
| FePi % | FGF23 | PTH | 0.035 (0.01), 0.014 | 0.007 (0.02), 0.78 | 0.136 | 0.0035 (0.01), 0.84 | 0.136 |
| FePi % | FGF23 | PTH, 1,25(OH)2D | 0.033 (0.01), 0.029 | -0.003 (0.03), 0.901 | 0.237 | -0.002 (0.01), 0.906 | 0.237 |
| FECa% | PTH | -0.008 (0.004), 0.065 | -0.008 (0.005), 0.13 | 0.76 | -0.011 (0.005), 0.052 | 0.603 | |
| FECa% | PTH | 1,25(OH)2D | -0.008 (0.004), 0.058 | -0.010 (0.004), 0.058 | 0.591 | -0.010 (0.004), 0.058 | 0.591 |
| FECa% | 1,25(OH)2D | PTH | 0.003 (0.005), 0.536 | -0.01 (0.007), 0.168 | 0.188 | -0.01 (0.007), 0.168 | 0.188 |