Table 4.
Coefficient of Determination (R2) Comparing Neuropathy Scales to IENFD and Electrophysiology
Small Fiber Function | Large Fiber Function | |||||||
---|---|---|---|---|---|---|---|---|
| ||||||||
IENFD (Distal Leg) | IENFD (Thigh) | QSART | CDT | Sural SNAP Amp. | Fibular MCV | VDT | ||
Distal Leg | Foot | |||||||
mTCNS | 0.0028 (P=0.686) | 0.0150 (P=0.360) | 0.0079 (P=0.687) | 0.0956 (P=0.117) | 0.0009 (P=0.907) | 0.0370 (P=0.096) | 0.0642 (P=0.032) | 0.1530 (P=0.048) |
TNSc | 0.0300 (P=0.186) | 0.0116 (P=0.421) | 0.0078 (P=0.688) | 0.2020 (P=0.019) | 0.0080 (P=0.724) | 0.2320 (P<0.001) | 0.1870 (P<0.001) | 0.3540 (P=0.001) |
NISLL | 0.0000 (P=0.996) | 0.0003 (P=0.898) | 0.0686 (P=0.227) | 0.2420 (P=0.011) | 0.0242 (P=0.551) | 0.2120 (P<0.001) | 0.2780 (P<0.001) | 0.3360 (P=0.002) |
ENS | 0.0049 (P=0.594) | 0.0044 (P=0.620) | 0.0920 (P=0.159) | 0.2350 (P=0.010) | 0.0081 (P=0.722) | 0.1940 (P<0.001) | 0.2120 (P<0.001) | 0.4050 (P<0.001) |
UENS | 0.0018 (P=0.751) | 0.0037 (P=0.647) | 0.1030 (P=0.135) | 0.1910 (P=0.023) | 0.0003 (P=0.942) | 0.1590 (P<0.001) | 0.2490 (P<0.001) | 0.3250 (P=0.002) |
MDNS | 0.0002 (P=0.923) | 0.0005 (P=0.871) | 0.1020 (P=0.137) | 0.2670 (P=0.006) | 0.00133 (P=0.886) | 0.249 (P<0.001) | 0.3220 (P<0.001) | 0.3100 (P=0.003) |
NDS | 0.0044 (P=0.643) | 0.0016 (P=0.785) | 0.0017 (P=0.850) | 0.1440 (P=0.051) | 0.0343 (P=0.462) | 0.1790 (P<0.001) | 0.2690 (P<0.001) | 0.3630 P=(0.001) |
IENFD = intraepidermal nerve fiber density, QSART = quantitative sudomotor axon reflex test, CDT = cold detection threshold,
SNAP Amp. = sensory nerve action potential amplitude, MCV=motor conduction velocity, VDT = vibration detection threshold.