Table 4. Bone densitometric and microarchitectural variables by the HR-pQCT in women with systemic sclerosis and in controls*.
| Variables | Patients (n=33) | Controls (n=33) | p value (adjusted for BMI) |
|---|---|---|---|
| Distal radius | |||
| Dcort (mg HA/cm3) | 836.5 ± 86.7 | 826.3 ± 79.6 | 0.270 |
| Dtrab (mg HA/cm3) | 126.5 ± 41.9 | 153.8 ± 42.4 | < 0.02 |
| D100 (mg HA/cm3) | 287.8 ± 75.8 | 300.7 ± 70.8 | 0.371 |
| Dinn (mg HA/cm3) | 86.7 ± 45.5 | 115.3 ± 43.3 | < 0.02 |
| Dmeta (mg HA/cm3) | 183.9 ± 39.1 | 209.5 ± 43.0 | < 0.02 |
| Ct.Th (mm) | 0.7 ± 0.22 | 0.70 ± 0.19 | 0.306 |
| BV/TV | 0.1 ± 0.04 | 0.13 ± 0.03 | < 0.02 |
| Tb.N (1/mm) | 1.6 ± 0.38 | 1.72 ± 0.33 | 0.081 |
| Tb.Th (mm) | 0.067 ± 0.01 | 0.073 ± 0.01 | < 0.02 |
| Tb.Sp (mm) | 0.62 ±0.23 | 0.53 ± 0.16 | 0.073 |
| Tb1.NSD (mm) | 0.32 ± 0.23 | 0.27 ± 0.17 | 0.243 |
| Tibia | |||
| Dcort (mg HA/cm3) | 815.5 ± 71.8 | 802.8 ± 83.7 | 0.165 |
| Dtrab (mg HA/cm3) | 143.3 ± 44.4 | 170.8 ± 36.8 | < 0.02 |
| D100 (mg HA/cm3) | 257.2 ± 62.7 | 275.5 ± 53.5 | 0.182 |
| Dinn (mg HA/cm3) | 98.3 ± 48.2 | 128.1 ± 39.9 | < 0.02 |
| Dmeta (mg HA/cm3) | 209.5 ± 43.4 | 233.7 ± 34.4 | < 0.02 |
| Ct.Th (mm) | 0.98 ± 0.26 | 0.97 ± 0.30 | 0.343 |
| BV/TV | 0.12 ± 0.04 | 0.14 ± 0.03 | < 0.02 |
| Tb.N (1/mm) | 1.57 ± 0.33 | 1.76 ± 0.27 | < 0.02 |
| Tb.Th (mm) | 0.08 ± 0.02 | 0.08 ± 0.01 | 0.153 |
| Tb.Sp (mm) | 0.60 ± 0.18 | 0.51 ± 0.13 | 0.021 |
| Tb1.NSD (mm) | 0.32 ± 0.21 | 0.29 ± 0.31 | 0.385 |
*
Results expressed as the mean ± standard deviation (SD) values of the measured parameters. vBMD = volumetric bone mineral density; Dtrab = volumetric trabecular bone mineral density; Dinn = inner trabecular bone density; Dmeta = metatrabecular bone density; Dcort = volumetric cortical bone mineral density; D100 = total volumetric bone mineral density; Tb.Th = trabecular thickness; Tb.N = trabecular number; Tb.Sp = trabecular separation; Ct.Th = cortical thickness; Tb1.NSD = intra-distribution individual separation; BV/TV = trabecular bone volume.