Table 1. Correlation between the mRNA expressions of SPON2 and clinicopathological variables in patients with colorectal cancer revealed by data-mining of Oncomine gene array datasets.

Dataseta	Clinicopathological parameters	Total cases	SPON2 expression		χ2	p value
			Low-than-median	High-than-median
Bittner colon
	Dukes Stage
	A	49	34	15	13.514	0.001
	B	101	43	58
	C-D	87	33	54
	M stage
	M0	240	112	128	3.976	0.046
	M1	88	52	36
	Stage
	0-I	52	37	15	16.96	0.001
	II	103	42	61
	III	85	37	48
	IV	88	52	36
	T stage
	Tis-T1	15	12	3	13.852	0.003
	T2	55	35	20
	T3	220	95	125
	T4	28	12	16
	Years of Tobacco Use
	None	17	4	13	Fisher's Exact Test	0.047
	0~65	187	89	98
Jorissen Colorectal 3
	Dukes Stage				11.337	0.01
	A	24	18	6
	B	54	28	26
	C	43	14	29
	D	33	17	16
Gaedcke Colorectal
	Sex				8.021	0.005
	Male	44	17	27
	Female	21	16	5
Tsuji Colorectal
	Sex				3.967	0.046
	Male	54	23	31
	Female	29	19	10

^aThe analysis was performed using datasets from the Oncomine cancer gene expression microarray DB (https://www.oncomine.org/resource/login.html).