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A. MMP3 expression in parental CMS4 cells after stable MMP3 knockdown vs. SC, as shown by qPCR. B. Tumor growth illustrated for the indicated cell line (n = 16 mice per tumor cell line). C. Ectopic overexpression of MMP3 in CMS4 cells as shown at RNA (qPCR, upper panel) or protein (ELISA, lower panel) levels. D. Tumor growth in wild-type mice (n = 15 per tumor cell line) or SCID mice (n = 5 per tumor cell line). *P < 0.05.
