Table 5. Associations between variant H19 rs217727 and rs2839698 genotypes and clinicopathologic characteristics of gastric cancer.
| Variable | (CT + TT) and CC for rs217727 | Allelic odds ratios and 95% confidence intervals for rs217727 | (CT + TT) and CC for rs2839698 | Allelic odds ratios and 95% confidence intervals for rs2839698 | ||||
|---|---|---|---|---|---|---|---|---|
| CT + TT, N | CC, N | Adjusted OR (95% CI)a | P value | CT + TT, N | CC, N | Adjusted OR (95% CI)a | P value | |
| Tumor differentiation | ||||||||
| Well | 15 | 5 | 1.00 | 14 | 6 | 1.00 | ||
| Moderate | 86 | 37 | 0.95 (0.31-2.94) | 0.926 | 64 | 59 | 0.41 (0.14-1.18) | 0.098 |
| Poor | 239 | 118 | 0.70 (0.25-1.99) | 0.502 | 172 | 185 | 0.38 (0.14-1.03) | 0.058 |
| Depth of tumor infiltration | ||||||||
| T1 | 68 | 24 | 1.00 | 47 | 45 | 1.00 | ||
| T2 | 43 | 15 | 0.97 (0.44-2.13) | 0.935 | 23 | 35 | 0.61 (0.30-1.24) | 0.171 |
| T3 | 110 | 48 | 0.76 (0.42-1.37) | 0.356 | 80 | 78 | 0.98 (0.58-1.67) | 0.955 |
| T4 | 119 | 73 | 0.63 (0.36-1.11) | 0.109 | 100 | 92 | 1.00 (0.60-1.66) | 0.997 |
| Lymph node metastasis | ||||||||
| Negative | 121 | 49 | 1.00 | 88 | 82 | 1.00 | ||
| Positive | 219 | 111 | 0.80 (0.53-1.20) | 0.277 | 162 | 168 | 0.91 (0.63-1.33) | 0.633 |
| Localization | ||||||||
| Cardia | 152 | 69 | 1.00 | 116 | 105 | 1.00 | ||
| Noncardia | 188 | 91 | 0.91 (0.62-1.34) | 0.648 | 134 | 145 | 0.89 (0.62-1.28) | 0.527 |
a
Adjusted for age, sex, smoking status, residence, hypertension, and diabetes.