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. 2015 Mar 10;6(17):15652–15661. doi: 10.18632/oncotarget.3404

Figure 6. Metformin induces a state of energy deficiency, which correlates with a decrease in lipogenesis.

Figure 6

(A, B) LNCaP and DU145 were treated with increasing concentrations of metformin (0.25 to 5 mM). The ATP content (left panel), expressed as the % of the control, and lipogenesis were monitored. The correlation between the lipogenesis and the ATP content is shown in the left panel. The results are representative of three independent experiments.