Table 3. The univariate and the multivariate cox proportional hazard regression analyses for patients' survival in France cohort.
| Parameters (n = 246) | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95%CI) | p Value | HR (95%CI) | p Value | |
| Age (years) | 0.997 (0.980–1.015) | 0.756 | 0.990 (0.969–1.010) | 0.328 |
| ER status (+/–) | 0.687 (0.440–1.072) | 0.098 | 0.977 (0.337–2.833) | 0.965 |
| PR status (+/–) | 0.816 (0.524–1.270) | 0.368 | 1.349 (0.527–3.455) | 0.533 |
| Lymph node (+/–) | 1.493 (0.952–2.341) | 0.081 | 1.357 (0.794–2.317) | 0.264 |
| Grade (1, 2, 3) | 1.592 (1.159–2.188) | 0.004 | 0.912 (0.605–1.376) | 0.661 |
| P53 status (yes/no) | 1.814 (1.100–2.991) | 0.020 | 1.378 (0.792–2.399) | 0.257 |
| Mol_Sub (I, II, III, IV, V, VI) | 1.037 (0.875–1.229) | 0.677 | 1.799 (1.272–2.544) | 0.001 |
| 92-probe signature (high/low) | 1.927 (1.237–3.002) | 0.004 | 7.125 (2.462–20.618) | <0.001 |
HR, hazard ratio; CI, confident interval; ER, estrogen receptor; PR, progesterone receptor; Mol_Sub, molecular subtype; A low risk was defined as a prognostic index less than or equal to −0.272144, and a high risk as a PI higher than −0.272144.