Table 5. Toxicities of patients with R/SP-MLNMs treated with SRT.
Group A, n (%) | Group B, n (%) | Total, n (%) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Acute toxicities | Any Grade | Grade 3 | Grade 4 | Grade 5 | Any Grade | Grade 3 | Grade 4 | Grade 5 | Any Grade | Grade 3 | Grade 4 | Grade 5 |
Pneumonitis | 0 | 0 | 0 | 0 | 1 (6) | 0 | 0 | 0 | 1 (3) | 0 | 0 | 0 |
Esophagitis | 1 (6) | 0 | 0 | 0 | 1 (6) | 1 (6) | 0 | 0 | 3 (9) | 1 (3) | 0 | 0 |
Tracheitis | 0 | 0 | 0 | 0 | 2 (12) | 2 (12) | 0 | 0 | 2 (6) | 2 (6) | 0 | 0 |
Chest pain | 0 | 0 | 0 | 0 | 1 (6) | 0 | 0 | 0 | 1 (3) | 0 | 0 | 0 |
Agranulocytosis | 0 | 0 | 0 | 0 | 1 (6) | 0 | 0 | 0 | 1 (3) | 0 | 0 | 0 |
Thrombocytopenia | 0 | 0 | 0 | 0 | 1 (6) | 0 | 0 | 0 | 1 (3) | 0 | 0 | 0 |
Late toxicities | ||||||||||||
Tachycardia | 0 | 0 | 0 | 0 | 1 (6) | 0 | 0 | 0 | 1 (3) | 0 | 0 | 0 |
Lung fibrosis | 0 | 0 | 0 | 0 | 1 (6) | 0 | 0 | 0 | 1 (3) | 0 | 0 | 0 |
Tracheoesophageal fistula | 0 | 0 | 0 | 0 | 1 (6) | 0 | 0 | 1 (6) | 1 (3) | 0 | 0 | 1 (3) |
Esophageal-mediastinal fistula | 0 | 0 | 0 | 0 | 1 (6) | 0 | 0 | 1 (6) | 1 (3) | 0 | 0 | 1 (3) |
Note: Group A: Patients with R/SP-MLNMs who received treatment including surgery and/or chemotherapy, but not radiation therapy; Group B: Patients with R/SP-MLNMs who received treatment including surgery and/or chemotherapy, and radiation therapy
Percent was calculated based on the total enrolled in each group (group A = 16, group B = 17) or the total study (33).