Table 4. Multivariate Analysis.
Factor | N | RR (95% CI) | P Value |
---|---|---|---|
NRM | |||
Main effect | |||
FDG-PET− | 177 | 1 | |
FDG-PET+ | 156 | .754 (.479-1.185) | .2202 |
Donor type | |||
HLA-identical sibling | 120 | 1 | |
Cord blood | 53 | 2.691 (1.2-6.032) | .0162 |
Unrelated | 160 | 3.595 (1.964-6.583) | <.0001 |
Stem cell source | |||
Bone marrow | 18 | 1 | |
Peripheral blood | 262 | .33 (.16-.67) | .0025 |
Relapse/progression | |||
Main effect | |||
FDG-PET− | 177 | 1 | |
FDG-PET+ | 156 | 1.862 (1.263-2.745) | .0017 |
Histology | |||
FL | 104 | 1 | |
DLBCL | 82 | 2.365 (1.378-4.059) | .0018 |
MCL | 69 | 2.122 (1.209-3.726) | .0088 |
T and NK neoplasm | 78 | 1.882 (1.051-3.369) | .0333 |
Prior auto transplantation | |||
Yes | 66 | 1 | |
No | 267 | .578 (.38-.881) | .0109 |
Therapy failure (PFS) | |||
Main effect | |||
FDG-PET− | 177 | 1 | |
FDG-PET+ | 156 | 1.297 (.966-1.741) | .0833 |
Donor type | |||
HLA-identical sibling | 120 | 1 | |
Cord blood | 53 | 1.896 (1.228-2.929) | .0039 |
Unrelated | 160 | 1.521 (1.083-2.136) | .0155 |
Stem cell source | |||
Bone marrow | 18 | 1 | |
Peripheral blood | 262 | .54 (.3-.5) | .03 |
Histology | |||
FL | 104 | 1 | |
DLBCL | 82 | 2.094 (1.401-3.131) | .0003 |
MCL | 69 | 1.873 (1.23-2.853) | .0035 |
T and NK neoplasm | 78 | 1.548 (.995-2.408) | .0527 |
Mortality (OS) | |||
Main effect | |||
FDG-PET− | 177 | 1 | |
FDG-PET+ | 159 | 1.321 (.946-1.844) | .1028 |
Donor type | |||
HLA-identical sibling | 122 | 1 | |
Cord blood | 53 | 2.098 (1.266-3.476) | .004 |
Unrelated | 161 | 2.064 (1.379-3.09) | .0004 |
Stem cell source | |||
Bone marrow | 18 | 1 | |
Peripheral blood | 262 | .38 (.21-.67) | .0008 |
Histology | |||
FL | 104 | 1 | |
DLBCL | 85 | 2.393 (1.489-3.846) | .0003 |
MCL | 69 | 1.844 (1.118-3.041) | .0166 |
T and NK neoplasm | 78 | 1.706 (1.01-2.883) | .0458 |
Conditioning regimen | |||
Myeloablative | 90 | 1 | |
Non-myeloablative/RIC | 246 | .642 (0.447-0.921) | .0161 |