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LD50 determination in mice
| Group | n | Dose (mg/kg body weight) | No. of deaths | % Mortality |
|---|---|---|---|---|
| 1 | 4 | 50 | 0/4 | 0 |
| 2 | 4 | 90 | 1/4 | 25 |
| 3 | 4 | 162 | 1/4 | 25 |
| 4 | 4 | 292 | 4/4 | 100 |
| 5 | 4 | Control | – | 0 |
Log m=log D a+d. (f+1).
Log m=log 50+log 1.8 (1+1)=2.209245.
LD50 (i.p.)=161.9 mg/kg.
