Table 5. The association between acute insular stroke and time to relapse (in days) using crude and multivariable (adjusted) Cox proportional hazards modeling (n = 132).
| Model | Primary exposure Covariates |
HR | 95% CI | P |
|---|---|---|---|---|
| Crude | Acute insular infarct | 0.37 | 0.19 - 0.73 | <0.01 |
| Adjusted | Acute insular infarct | 0.48 | 0.24 - 0.98 | 0.04 |
| Age | 1.00 | 0.97 - 1.02 | 0.73 | |
| Baseline FTND | 1.08 | 0.95 - 1.24 | 0.24 | |
| NIHSS score | 0.95 | 0.90 - 1.00 | 0.06 | |
| Post-admission NRT/ drug use | 1.35 | 0.82 - 2.21 | 0.24 | |
| Mesocorticolimbic infarct | 0.73 | 0.41 - 1.27 | 0.26 | |
| Intent to quit | 0.63 | 0.31 - 1.26 | 0.19 |
HR, Hazard Ratio; CI, Confidence Interval; FTND, Fagerström Test for Nicotine Dependence; NIHSS, National Institutes of Health Stroke Scale; NRT, Nicotine Replacement Therapy.