Skip to main content
. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Behav Brain Res. 2015 Jun 20;292:305–315. doi: 10.1016/j.bbr.2015.05.039

Figure 4. Sign-tracking duration on the final testing session in male (M) and female (F) mice from the A/J, C57BL/6J, 129S1/SvImJ, NOD/ShiLtJ, and CAST/EiJ inbred strains.

Figure 4

Male CAST/EiJ mice in the paired condition (Q) exhibited robust sign-tracking as indicated by a significantly greater sign-tracking duration relative to unpaired controls (R) and during trials relative to inter-trial intervals. Male NOD/ShiLtJ mice in the paired condition (M) exhibited robust sign-tracking as indicated by a significantly greater sign-tracking duration relative to unpaired controls (N). In contrast to male CAST/EiJ mice, male NOD/ShiLtJ mice in the paired condition approached and attempted to reach the retracted lever during inter-trial intervals as indicated by a significantly greater sign-tracking duration during inter-trial intervals relative to that of unpaired controls (N). Male C57BL/6J (E) and female A/J (C) mice in the paired condition exhibited a significantly greater sign-tracking duration during trials relative to inter-trial intervals. This indicates significant but less robust sign-tracking in male C57BL/6J and female A/J mice relative to male CAST/EiJ and NOD/ShiLtJ mice. Mice from other strain-sex subgroups in the paired condition and mice in the unpaired condition did not exhibit significant sign-tracking. Sign-tracking duration on the final session was quantified by video analysis.

* p < .05, trial vs ITI

† p < .05, paired vs unpaired