Table 1.
Association statistics between thyroid cancer risk and rs6983267 in the three different populations investigated in the present study.
| Study | Genotypes / Risk Allele | Number of cases (frequency) | Number of controls (frequency) | Odds Ratio (95% CI) | P value |
|---|---|---|---|---|---|
| BritishIsles | TT | 539 (0.231) | 1709 (0.273) | Reference | |
| GT | 1150 (0.492) | 3087 (0.493) | 1.18 (1.05–1.33) | 5.74 × 10−3 | |
| GG | 649 (0.278) | 1460 (0.233) | 1.41 (1.23–1.61) | 5.06 × 10−7 | |
| G allele | 2448 (0.524) | 6007 (0.480) | 1.19 (1.11–1.27) | 4.03 × 10−7 | |
| Colombia | TT | 45 (0.160) | 183 (0.204) | Reference | |
| GT | 147 (0.523) | 471 (0.524) | 1.27 (0.87–1.85) | 0.213 | |
| GG | 89 (0.317) | 245 (0.273) | 1.48 (0.98–2.22) | 0.060 | |
| G allele | 325 (0.578) | 961 (0.534) | 1.19 (0.99–1.44) | 0.069 | |
| Japan | TT | 175 (0.390) | 645 (0.454) | Reference | |
| GT | 210 (0.469) | 603 (0.425) | 1.28 (1.02–1.61) | 0.032 | |
| GG | 63 (0.140) | 172 (0.121) | 1.35 (0.97–1.88) | 0.077 | |
| G allele | 336 (0.375) | 947 (0.333) | 1.20 (1.03–1.41) | 0.022 |