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. Author manuscript; available in PMC: 2016 Aug 1.

Published in final edited form as: Endocr Relat Cancer. 2015 Aug 19;22(5):841–849. doi: 10.1530/ERC-15-0081

Table 2.

Association statistics between TC risk and rs6983267 in different subtypes of TC tested in British Isles and Colombia

Subtype	British Isles					Colombia
Subtype	Genotypes	No of cases (frequency)	No of Controls (frequency)	OR (95% CI)	P value	No of cases (frequency)	No of Controls (frequency)	OR (95% CI)	P value
PTC	TT	270 (0.226)	1,709 (0.273)	Reference		24 (0.140)	183 (0.204)	Reference
	GT	595 (0.498)	3,087 (0.493)	1.22 (1.04–1.43)	0.012	95 (0.552)	471 (0.524)	1.54 (0.95–2.48)	0.078
	GG	330 (0.276)	1,460 (0.233)	1.43 (1.20–1.71)	6.25 × 10⁻⁵	53 (0.308)	245 (0.273)	1.62 (0.96–2.72)	0.070
	G allele	1,255 (0.525)	6,007 (0.480)	1.20 (1.10–1.31)	5.50 × 10⁻⁵	201 (0.584)	961 (0.534)	1.21 (0.96–1.53)	0.107
FV+FTC	TT	174 (0.230)	1,709 (0.273)	Reference		21 (0.193)	183 (0.204)	Reference
	GT	367 (0.485)	3,087 (0.493)	1.17 (0.97–1.41)	0.110	52 (0.477)	471 (0.524)	0.96 (0.56–1.64)	0.887
	GG	215 (0.284)	1,460 (0.233)	1.45 (1.17–1.79)	6.34 × 10⁻⁴	36 (0.330)	245 (0.273)	1.28 (0.72–2.27)	0.396
	G allele	797 (0.527)	6,007 (0.480)	1.21 (1.09–1.34)	5.50 × 10⁻⁴	124 (0.569)	961 (0.534)	1.15 (0.87–1.53)	0.337