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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: FEBS J. 2015 Jul 14;282(17):3395–3411. doi: 10.1111/febs.13350

Figure 4. Multiple Correspondence Analysis (MCA) of the presence/absence of essential genes in NOGs.

Figure 4

MCA analysis of essential gene sets based on the presence/absence profiles of each mapped NOG. The first two dimensions obtained in MCA were dominated by one or two samples and therefore, are not very useful for separation purposes. Dimensions 3 and 4 allowed an evolutionarily coherent clustering, while still accounting for a significant amount of variance. For abbreviations of in vitro experiments refer to Figure 1. For in vivo experiments: ftula-invivo (F. tularensis novicida U112, in vivo); mtube-invivo (Mycobacterium tuberculosis H37Rv, in vivo); and mtube-mac (Mycobacterium tuberculosis H37Rv, macrophages). For color codes, refer to Figure 3.