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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: FEBS J. 2015 Jul 1;282(17):3323–3333. doi: 10.1111/febs.13345

Fig. 1.

Fig. 1

Recombination targets used in the study. (A) FRT, shown as a reference, consists of two inverted 13 bp Flp binding elements flanking the 8-bp strand exchange region (spacer). (B) FRT-like sequence FL-IL10A. (C) The hybrid FRT/FL-IL10A sequence is composed of the left recombinase binding element of FRT and right recombinase binding element of FL-IL10A separated by the spacer from FL-IL10A. The positions within the recombinase binding elements that differ from the corresponding positions in FRT are indicated by lower case red letters. (D) loxP consists of two inverted 14 bp Cre binding elements flanking the 6-bp strand exchange region. Points of single-stranded DNA exchange in FRT and loxP are indicated by vertical arrows.