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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Osteoarthritis Cartilage. 2015 Apr 29;23(9):1523–1531. doi: 10.1016/j.joca.2015.04.019

Fig. 6.

Fig. 6

HB-EGF inhibits OP-1 mediated proteoglycan synthesis. Chondrocytes were stimulated overnight with 100ng/mL OP-1 or the combination of OP-1 and 10ng/mL HB-EGF. Proteoglycan synthesis was measured using [35S]sulfate incorporation and DNA was analyzed with a PicoGreen assay. Results were normalized to unstimulated controls set as 1 and are mean±sem of four independent donors.