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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Osteoarthritis Cartilage. 2015 Apr 29;23(9):1523–1531. doi: 10.1016/j.joca.2015.04.019

Fig. 7.

Fig. 7

HB-EGF inhibits OP-1 stimulation of aggrecan but not COL2A1, ID1, or SMAD6 expression. Chondrocytes were treated overnight with control media, 10ng/ml HB-EGF, 100ng/ml OP-1, or the same amounts of HB-EGF + OP-1. RNA was isolated and used for quantitative PCR with primers for aggrecan (A), COL2A1 (B), ID1 (C), and SMAD6 (D). Results shown are the mean±sem of samples from four independent donors.