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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Structure. 2015 Jul 23;23(9):1573–1583. doi: 10.1016/j.str.2015.06.015

Figure 7.

Figure 7

The D265A Fc variant retains significant contact between the polypeptide and N-glycan termini as observed with the (6) and (6') galactose residues. 1H-13C HSQC spectra of (A) IgG1 Fc wt and (B) D265A variant. N-glycans were remodeled to display the G2F glycoform with 13C2-galactose. Positions of Fc wt peaks are highlighted by “+”. Resonance frequencies consistent with an exposed and unrestricted N-glycan are labeled “e” (Subedi et al., 2014).