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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Aliment Pharmacol Ther. 2015 Aug 4;42(7):922–933. doi: 10.1111/apt.13346

Figure 3.

Figure 3

Urease activity of permeabilized H. pylori is decreased at both pH 4.5 and pH 7.4 in the presence of CBS. Urease activity was measured quantitatively by using [14]C-labeled urea and detecting output of 14C-labeled carbon dioxide. Results are normalized to total protein in each sample. Bacteria were permeabilized with C12E8, allowing free access of urea and bismuth to the bacterial cytoplasm. N=6, error bars represent SEM, p values calculated by t-test, *p<0.05.