Table 2.
Effect of B. longum on blood serum parameters.
| Serum parameters | Sham | OVX | OVX + B. longum | p value |
|---|---|---|---|---|
| OC (ng/mL) | 184.61 ± 6.93a | 76.81 ± 6.44c | 101.31 ± 9.21b | 0.001 |
| CTX (ng/mL) | 113.77 ± 20.02b | 249.28 ± 7.57a | 147.05 ± 6.25b | 0.009 |
| Ca (mmol/L) | 2.27 ± 0.12 | 2.23 ± 0.12 | 2.27 ± 0.06 | 0.939 |
| Mg (mmol/L) | 0.97 ± 0.07 | 0.89 ± 0.09 | 0.91 ± 0.06 | 0.751 |
Ten-week-old female Sprague-Dawley rats were supplemented with 1 mL of B. longum (108–109 CFU) once a day for 16 weeks, starting 2 weeks after surgery, while sham and OVX groups received 1 mL of demineralized water. At the end of the study, the blood serum of the rats was analyzed for osteocalcin (OC), C-terminal telopeptide (CTX), calcium (Ca), and magnesium (Mg). Values represent the mean ± standard error of the mean (SEM) (n = 8 in each group).
abcValues with different letters in the same row are significantly different at p < 0.05 based on one-way ANOVA, followed by Tukey's post hoc test.