Table 3.
The ROC analysis for differentiating the PD patients from the nPD group and its subgroups based on the SRR calculated with our novel method that uses inversely transformed striatal and reference VOIs.
| Versus nPD group | Versus healthy controls | Versus essential tremor subjects | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cutoff | Sensitivity | Specificity | Accuracy | AUC | Cutoff | Sensitivity | Specificity | Accuracy | AUC | Cutoff | Sensitivity | Specificity | Accuracy | AUC | |
| PD group | 1.73 | 92.1 | 90.2 | 91.8 | 0.94 | 1.76 | 93.2 | 96.4 | 93.4 | 0.98 | 1.67 | 87.7 | 84.8 | 87.4 | 0.91 |
| Group≤2 | 1.73 | 88.1 | 90.2 | 88.8 | 0.91 | 1.76 | 90.7 | 96.4 | 91.8 | 0.97 | 1.73 | 88.1 | 81.8 | 86.8 | 0.87 |
| Group3–5 | 1.73 | 89.0 | 90.2 | 89.4 | 0.93 | 1.75 | 90.0 | 96.4 | 91.4 | 0.97 | 1.73 | 90.0 | 81.8 | 88.0 | 0.90 |
| Group6–10 | 1.66 | 94.3 | 91.8 | 93.2 | 0.96 | 1.72 | 97.7 | 100.0 | 98.3 | 0.99 | 1.66 | 94.3 | 84.8 | 91.7 | 0.93 |
| Group≥11 | 1.51 | 93.3 | 95.1 | 94.2 | 0.97 | 1.68 | 96.7 | 100.0 | 97.7 | 0.98 | 1.47 | 91.7 | 97.0 | 93.5 | 0.97 |