Table 2.
Biochemical data of the study participants.
| C (n = 10) |
P-Ch 0 (n = 22) |
P-Ch A (n = 14) |
P-Ch B (n = 25) |
P-Ch C (n = 24) |
|
|---|---|---|---|---|---|
| Bilirubin (mg/dL) | 0.64 ± 0.22 | 2.66 ± 0.82 | 2.7 ± 0.95 | 5.58 ± 0.82 | 9.71 ± 0.98 |
| Albumin (g/dL) | 5.23 ± 0.54 | 4.20 ± 0.74 | 4.00 ± 0.67 | 3.80 ± 0.84 | 2.42 ± 0.48 |
| ALT (U/L) | 19.24 ± 8.56 | 34.10 ± 8.21 | 56.63 ± 15.51 | 63.19 ± 10.38 | 70.31 ± 18.22 |
| AST (IU/L) | 17.81 ± 5.030 | 42.51 ± 26.45 | 53.50 ± 27.36 | 152.9 ± 114.3 | 190.2 ± 255.1 |
| AST/ALT ratio | 0.96 ± 0.21 | 1.96 ± 1.07 | 2.67 ± 2.22 | 2.83 ± 1.35 | 3.39 ± 1.73 |
| GGTP (IU/L) | 20.40 ± 8.96 | 234.81 ± 46.95 | 313.75 ± 27.96 | 642.24 ± 70.04 | 749.48 ± 72.55 |
| Urea (mg/dL) | 24.40 ± 10.07 | 35.45 ± 8.62 | 38.77 ± 6.98 | 44.81 ± 8.54 | 51.25 ± 5.39 |
| Blood platelets (K/μL) | 340.2 ± 7.96 | 320.95 ± 6.46 | 166.75 ± 11.96 | 135.46 ± 12.28 | 105.33 ± 7.02 |
| INR | 1.26 ± 0.16 | 1.24 ± 0.16 | 1.30 ± 0.21 | 1.39 ± 0.23 | 2.01 ± 0.90 |
| MCV (fl) | 86.00 ± 7.26 | 97.31 ± 7.24 | 95.97 ± 9.36 | 97.09 ± 6.27 | 103.07 ± 6.09 |
| Na (mmol/L) | 139.50 ± 3.44 | 133.56 ± 4.77 | 129.75 ± 10.50 | 134.05 ± 4.78 | 131.85 ± 8.41 |
| K (mmol/L) | 4.17 ± 0.32 | 4.02 ± 0.70 | 3.59 ± 0.42 | 4.07 ± 0.77 | 3.86 ± 0.60 |
Key: data are expressed as mean ± SD.
P-Ch 0: alcoholics without liver cirrhosis; P-Ch stages A, B, and C: alcoholics with liver cirrhosis Pugh-Child stages A–C; C: healthy controls.
Normal range: bilirubin (0–1.2 mg/dL), albumin (3.5–5.20 g/dL), ALT (alanine aminotransferase) (5–40 U/L), AST (aspartate aminotransferase) (5–40 IU/L), GGTP (Gamma-glutamyl transpeptidase) (11–50 IU/L), urea (21–43 mg/dL), blood platelets (120–400 K/μL), INR (0.86–1.30), MCV (mean cell volume) (80–94 fl), Na (sodium) (136–145 mmol/L), and K (potassium) (3.5–5.1 mmol/L).