Table 2.
sGC activity of compound 10
| GC activator | Compound 10 IC50 (μM) ± SE |
Hill slope | |
|---|---|---|---|
| Cinaciguat | 1 μM | 37 ± 40 | 4 |
| 20 nM | 25 ± 4 | 4 | |
| ANP | 1 μM | 25 ± 13 | 1 |
| 10 nM | 21 ± 3 | 2 | |
| Basal | 15 ± 2 | 2 | |
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