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. 2015 Aug 6;6(8):e1845. doi: 10.1038/cddis.2015.200

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Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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MiR-587 decreases the effectiveness of 5-FU in the inhibition of tumor growth in vivo. Xenograft tumor growth curves (a), pictures of tumors taken on the same scale (b) and tumor weights (c) are shown. (d and e) Images of TUNEL (d) and Ki67 (e) staining of tumors are shown in the left panels. The images are representative of multiple fields of tumor sections from each group. Percentage of positive TUNEL (d) and Ki67 (e) staining cells were determined (right panels). The data are presented as the mean±S.E. *P<0.05, ***P<0.001. Scale bars, 25 μm