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. 2015 Aug 6;6(8):e1846. doi: 10.1038/cddis.2015.204

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Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Syncytial apoptosis map—cell fusion. Interaction between a HIV-1-infected cell (purple compartment) and a CD4⁺ healthy cell (green compartment). This part includes all the reactions leading to the activation of P2RY2 and PTK2B proteins, determining cell-to-cell fusion. Nuclei are denoted with blue contours, proteins are colored in green, genes are colored in yellow, viruses are colored in purple. Asterisks indicate non-official HGNC names. Please see Supplementary Information for more detailed map notion