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. 2015 Aug 6;6(8):e1842. doi: 10.1038/cddis.2015.205

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Copyright © 2015 Macmillan Publishers Limited

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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TIGAR expression in TAp73-null animals. (a) Left: Western blot analysis of TIGAR protein expression in organs of wild-type (WT) and TAp73^−/− mice. Right: Graph represents quantification of western blots with fold change compared with WT. (b) mRNA expression of TIGAR, p21 and TAp73 in organs of WT and TAp73^−/− mice. (c) Immunohistochemistry on small intestines from WT and TAp73^−/− animals 72 h after 10 Gy IR. Scale bar, 20 μm. Values represent mean±S.E.M. of three independent experiments. *P<0.05, **P<0.005 compared with WT. NS, not significant; WAT, white adipose tissue; BAT, brown adipose tissue