Figure 2. Temporal snapshots of Myosin-XV inside relatively short filopodia (<5 μm) at different times, with Myosin-XV labelled fluorescently in green (top panels), and respective concentration profiles at the bottom.

In (a) aggregates that form at the tip (black arrow) and move rearwards from the tip, in the form of isolated pulses and pulse trains. In (b) the tip region gets “filled” with motors (indicated by the red bar), develops undulations (TWs), and eventually initiates release of pulses (black arrow).