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. 2015 Sep 3;5:13497. doi: 10.1038/srep13497

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Copyright © 2015, Macmillan Publishers Limited

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The pericyte expression markers PDGFRß, NG2, and Desmin were significantly upregulated following CCI. mRNA analyses were carried out on days 1, 3, 5 and 7 following TBI (A). PDGFRß mRNA levels were found to increase significantly, starting on day 3 after CCI with a peak at day 5 (B). The pericyte marker NG2 was also upregulated upon CCI from days 3–7 (C). Here, maximum NG2 mRNA levels were detected 5 days after brain trauma induction. The pericyte marker Desmin was already significantly upregulated on day 1, reaching its maximum expression levels on day 3 after CCI (D). N = 8–10 animals per group; *P < 0.05; **P < 0.01; ***P < 0.001.