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. Author manuscript; available in PMC: 2016 Apr 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2015 Feb 21;284(2):180–187. doi: 10.1016/j.taap.2015.02.013

Figure 4. Clustering analysis of ALT, APAP adducts and miRNAs peak time from overdose subjects with multiple measures.

Figure 4

Overdose subjects were listed by alphabet (A-H) and days after APAP ingestion (day2 -7). For example, B_4 is sample collected from subject B at day 4 after APAP overdose. HCA analysis showing miR-122 peaks at similar time as ALT or APAP protein adducts, however, some miRNA levels precede those of ALT or APAP protein adducts.