Table 3.
Event Free and Overall Survival at 1 Year
| Arm | No. of Patients | EFS at 1 Year (%) | 95% CI | OS at 1 Year (%) | 95% CI |
|---|---|---|---|---|---|
| A, 3 mg/m2 | |||||
| Overall | 20 | 55.0 | 32.8 to 77.2 | 64.6 | 43.1 to 86.2 |
| Induction failure | 1 | 100 | — | 100 | — |
| Relapsed AML | 13 | 46.2 | 18.5 to 73.8 | 60.6 | 32.9 to 88.2 |
| Secondary AML | 6 | 66.7 | 28.2 to 100 | 66.7 | 28.2 to 100 |
| B, 2 mg/m2 | |||||
| Overall | 22 | 21.8 | 3.8 to 39.9 | 45.0 | 23.6 to 66.4 |
| Induction failure | 7 | 25.0 | 0 to 55.6 | 46.9 | 9.6 to 84.2 |
| Relapsed AML | 8 | 12.5 | 0 to 35.9 | 25.0 | 0 to 55.6 |
| Secondary AML | 6 | 33.3 | 0 to 71.8 | 66.7 | 28.2 to 100 |
Abbreviations: EFS, event-free survival; OS, overall survival; AML, acute myeloid leukemia.