Table 2. Geometric mean ratio (GMR) and the 90% CIs for metformin.

Parameter		GMR† (%)	90% CIs
Metformin	Cmax (µg/mL)	102.4	94.5 – 111.0
	AUC0–t (µg×h/mL)	107.1	100.1 – 114.7
	AUC0–∞ (µg×h/mL)	107.2	100.3 – 114.6

^†GMR represents geometric mean ratio of voglibose/metformin fixed-dose combination (test) to coadministered voglibose and metformin (reference) (test/reference). These estimates are obtained using least square means from the mixed effects model with the fixed effects for sequence, period and treatment, and a random effect for subjects within sequence.