Cardiovascular dysfunction |
• Shock |
|
• Use of continuous vasoactive drugs |
|
• Cardiac arrest |
|
• Cardio-pulmonary resuscitation |
|
• Severe hypoperfusion (lactate > 5 mmol/L or > 45 mg/dL) |
|
• Severe acidosis (pH < 7.1) |
Respiratory dysfunction |
• Acute cyanosis |
|
• Gasping |
|
• Severe tachypnea (respiratory rate > 40 bpm) |
|
• Severe bradypnea (respiratory rate < 6 bpm) |
|
• Severe hypoxemia (PAO2/FiO2 < 200 or O2 saturation < 90 % for ≥60 min) |
|
• Intubation and ventilation not related to anesthesia |
Renal dysfunction |
• Oliguria non responsive to fluids/diuretics |
|
• Dialysis for acute renal failure |
|
• Severe acute azotemia (creatinine ≥ 300 umol/ml or ≥ 3.5 mg/dL) |
Coagulation/hematologic dysfunction |
• Failure to form clots |
|
• Massive transfusion of blood or red cells (≥5 units) |
|
• Severe acute thrombocytopenia (<50,000 platelets/ml) |
Hepatic dysfunction |
• Jaundice in the presence of pre-eclampsia |
|
• Severe acute hyperbilirubinemia (bilirubin > 100 umol/L or > 6.0 mg/dL) |
Neurologic dysfunction |
• Prolonged unconsciousness (lasting ≥ 12 hours)/coma (including metabolic coma) |
|
• Stroke |
|
• Status epilepticus/uncontrollable fits |
|
• Total paralysis |
Uterine dysfunction |
• Hemorrhage or infection leading to hysterectomy |