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. 2015 Sep 3;17(1):234. doi: 10.1186/s13075-015-0757-4

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© Shock et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Inhibition of humoral immune response in Cynomolgus monkeys: comparison of antibody formats. Animals received a single i.v. dose of antibody or saline 2 days prior to administration of tetanus toxoid (TT); the doses were 20 mg/kg for the IgG antibodies and 40 mg/kg for the PEGylated formats (n = 6 for all groups). The IgG anti-TT titers in plasma samples were assessed from days 10 to 31