Fig. 4.

Enhanced expression between Q₅₆-YFP and Q₀-YFP yeast cells. a Network of genes up-regulated in Q₅₆-YFP expressing cells compared to Q₀-YFP expressing cells using the same color code as Fig. 2a. Hits with a p-value smaller than 0.05 were indicated by a greater font size (for details see Additional file 8). Blue frames highlight predicted co-regulated genes listed in Additional file 3. The smaller font size was additionally used for the predicted coregulators. Red boxes highlight clusters according to cellular pathways. b Analysis of predicted co-regulators within Fig. 4a. The line shows the number of genes within the respective category, while the vertical bar chart indicates the percentage of the genes predicted by the SPELL-correlations. If bars for all expression categories have the same height no significant enrichment in the predicted genes would be reported, which would indicate a non-significant clustering analysis