Fig. 4.

Schematic diagram of amino acid sequence variations in BHRF1 protein. The amino acid sequence of BHRF1 protein derived from B95-8 is listed. The previously identified BH1-3 domain are put into the rectangles. α2-α5 helices are underlined at the corresponding regions. Numbers indicate amino acid positions; asterisks indicate mutant amino acids. The mutated amino acid residues to B95-8 are indicated in boxes. Frequencies of the mutations were also showed