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MDS plot of codon usage differences for HPV genes within each genus. HPVs are classified by an unsupervised two-step clustering algorithm and visualized by MDS dimension reduction. The clusters are colored yellow (cluster1), blue (cluster 2), and green (cluster 3), respectively. Codes for genes: Squares, E6; diamonds, E7; triangles, E1; inverse triangles, E2; crosses, E4; stars, L2; circles, L1.
