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. 2015 Jul 10;7(8):2173–2187. doi: 10.1093/gbe/evv135

Table 1.

Levels of Variation in the Sequences of Genes and in Gene Content within the 14 Examined Species and Correlations between These Types of Variation

Species Name No. of Analyzed Genomes Minimal AAI Maximal Fluidity Spearman’s ρa % of Increase in Genomic Fluidity per 1% Decrease in AAI % of Increase in Genomic Fluidity per 1% Decrease in AAI for Strains with AAI >99.5%
Bacillus cereus 13 93.05 0.225 −0.843 (P ≪ 0.0001) 1.51 N/A
Campylobacter jejuni 13 95.72 0.279 −0.812 (P ≪ 0.0001) 4.89 7.32
Clostridium botulinum 10 95.60 0.191 −0.638 (P ≪ 0.0001) 2.65 N/A
Corynebacterium diphtheriae 13 98.00 0.147 −0.474 (P ≪ 0.0001) 4.95 N/A
Corynebacterium pseudotuberculosisb 15 98.59 0.103 −0.746 (P ≪ 0.0001) 4.03 15.46
Eschirechia coli–Shigella 60 97.37 0.287 −0.677 (P ≪ 0.0001) 5.66 13.65
Francisella tularensisb 12 98.84 0.168 −0.748 (P ≪ 0.0001) 6.33 8.95
Haemophilus influenzae 10 95.98 0.216 −0.417 (P = 0.0056) 2.34 N/A
Listeria monocytogenes 26 96.06 0.133 −0.825 (P ≪ 0.0001) 1.71 10.14
MTBCb 20 99.62 0.140 −0.820 (P ≪ 0.0001) 26.16 26.16
Neisseria meningitides 14 97.52 0.162 −0.785 (P ≪ 0.0001) 5.67 N/A
Pseudomonas aeruginosa 13 94.57 0.169 −0.759 (P ≪ 0.0001) 1.77 N/A
Streptococcus pneumonia 21 97.67 0.187 −0.567 (P ≪ 0.0001) 5.56 N/A
Yersinia pestisb 12 99.65 0.164 −0.632 (P ≪ 0.0001) 31.31 31.31

Note.—N/A denotes species that have few or no pairs of strains with AAI >99.5%.

aSpearman’s ρ coefficient calculated for correlation between AAI and genomic fluidity for considered bacterial species. P-value is shown in parentheses.

bClonal species.