Table 1.
Species Name | No. of Analyzed Genomes | Minimal AAI | Maximal Fluidity | Spearman’s ρa | % of Increase in Genomic Fluidity per 1% Decrease in AAI | % of Increase in Genomic Fluidity per 1% Decrease in AAI for Strains with AAI >99.5% |
---|---|---|---|---|---|---|
Bacillus cereus | 13 | 93.05 | 0.225 | −0.843 (P ≪ 0.0001) | 1.51 | N/A |
Campylobacter jejuni | 13 | 95.72 | 0.279 | −0.812 (P ≪ 0.0001) | 4.89 | 7.32 |
Clostridium botulinum | 10 | 95.60 | 0.191 | −0.638 (P ≪ 0.0001) | 2.65 | N/A |
Corynebacterium diphtheriae | 13 | 98.00 | 0.147 | −0.474 (P ≪ 0.0001) | 4.95 | N/A |
Corynebacterium pseudotuberculosisb | 15 | 98.59 | 0.103 | −0.746 (P ≪ 0.0001) | 4.03 | 15.46 |
Eschirechia coli–Shigella | 60 | 97.37 | 0.287 | −0.677 (P ≪ 0.0001) | 5.66 | 13.65 |
Francisella tularensisb | 12 | 98.84 | 0.168 | −0.748 (P ≪ 0.0001) | 6.33 | 8.95 |
Haemophilus influenzae | 10 | 95.98 | 0.216 | −0.417 (P = 0.0056) | 2.34 | N/A |
Listeria monocytogenes | 26 | 96.06 | 0.133 | −0.825 (P ≪ 0.0001) | 1.71 | 10.14 |
MTBCb | 20 | 99.62 | 0.140 | −0.820 (P ≪ 0.0001) | 26.16 | 26.16 |
Neisseria meningitides | 14 | 97.52 | 0.162 | −0.785 (P ≪ 0.0001) | 5.67 | N/A |
Pseudomonas aeruginosa | 13 | 94.57 | 0.169 | −0.759 (P ≪ 0.0001) | 1.77 | N/A |
Streptococcus pneumonia | 21 | 97.67 | 0.187 | −0.567 (P ≪ 0.0001) | 5.56 | N/A |
Yersinia pestisb | 12 | 99.65 | 0.164 | −0.632 (P ≪ 0.0001) | 31.31 | 31.31 |
Note.—N/A denotes species that have few or no pairs of strains with AAI >99.5%.
aSpearman’s ρ coefficient calculated for correlation between AAI and genomic fluidity for considered bacterial species. P-value is shown in parentheses.
bClonal species.